I'm 40, doing IVFdue to age and a mc at 10 weeks due to Trisomy18. IVF#1 with ICSI spring 2006 - 3 eggs retrieved, one transferred - BFN You are posting as a Guest without being logged in. Estrogen is administered during the luteal phase of the previous menstrual cycle to "prime" the FSH receptors which enhances the response to FSH. This is my first time posting and was hoping for some other stories like mine. He did say there are some studies that DHEA and CoQ10 could help, but the, Hi all. New doctor recommended EPP to promote more even follicle growth. This clinic is more generous with freezing, so they tested and froze a few other blasts as well, which the other clinic would have thrown out. Editorial Review Policy. Had three chromosomal miscarriages last year, moved on to IVF with intention of genetic testing but had to cancel cycle a few days in, E2 never got above 36 while on max dose of 300 Gonol f and 300 Menopur. The idea is to give your body about 5-7 days of Estrogen Priming. Join Tomato Lovers & Participate in the Ukrainian Tribute Growout! During cycle 1 you use OPKs to track your LH surge and ovulation. 1st IVF/ICSI age 41 : Gonal F 300; 3 eggs; 2 fertilised; transfer day 5; BFN Wow that did make a huge difference for you! Or are there different levels of this? It helps your lining and encourages your eggs to all grow at the same rate. From what I've seen on the boards, ladies get a higher number and higher quality. I was 41 at SG and they also put me on BCPs and i knew it was going to oversupress me -- and it did. Did not cover diagnostics like doppler test (40 copay but insurance might have covered this), communicable testing ($400 per person), and specialty meds . Why so many days of esterace( 15-16 days before starting/adding promethium for 10 days) then the stim cycle, 3. Just devastated with my results today so just want to cry it out and then I will respond to you. I just had my first IVF and it was unsuccesful. Does anyone have experience with this? We're not even 100% sure we are staying with my current clinic but I wanted to research ahead of time either way. I did a low stim ivf (225 menopur & 100 mg clomid) with human growth hormone which is what my fertilty clinic does for women over 40 and poor responders. As a result, its hard to correct for confounders like the fact that harder cases may (or in our minds, probably) had been given more drug and so the underlying condition, rather than the dose taken, contributed to the lower rates of success. I think you should ask your doctor though to make sure.Again, here is what happened to my protocolCycle day 1 - PeriodCycle day 24 (7 days post ovulation) - Start Estrace Cycle day 1 - Period Cycle day 2 - Last Estrace pill Cycle day 3 Blood work & ultrasound; antral follicle count. I was on the highest dosage of Gonal with that cycle. I was on bcps and Lupron the first ivf. No BCP - started my period, did cycle day 2 testing FSH was good (I had high a FSH of 15 so EPP helped that) then started meds. I understand the idea for the patch is to help time the growth of follicles vs. increase the number? BFP October 22!!!! This was all on the phone, so not 100 percent on what the protocol would be. Similarly, when an investigator named Revelli decided to swap out a few days of gonadotropin for clomid in this poor responder population in Italy (and thereafter resumed gonadotropin at low levels), he saw similar rates of success to more conventional levels of gonadotropin use. Pre-treatment is known to improve the response of the ovary to the stimulation cycle and also reduces the risk of ovarian cyst formation. Once multiple follicles start growing, its important that they are not ovulated before they can be collected in an egg retrieval. Very helpful! Went to retrieval anyway, did ICSI, but it didn't fertilize. To get FSH, patients take Gonal-F or Follistim (many consider them to be interchangeable) and to get FSH-plus-LH most women take Menopur (pretty much the only product on the market). I went to a UK FSH friendly (thank you joy for the recommendation) clinic for a consultation. I did estrogen and testosterone priming on my second ivf because I was oversuppressed during my first cycle. Heres an example from the same study. DS was born June 22nd, 2007!!!!! I was on BCP for 15 years and when I went off them I never got my period. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are used to stimulate the ovaries to recruit and develop more than one follicle. Group Black's collective includes Essence, The Shade Room and Naturally Curly. my RE is going back to the drawing board for my final IVF. 3rd IVF age 42 : Short protocal Menopur 375; so far on Day 4 scan 2 focilles again and some very small ones Whats important to stress here is that just because some low dose approaches drive comparable rates of success to conventional approaches, that doesnt mean all low-or-no dose approaches are effective. Today, most IVF cycles use a frozen transfer whereby embryos are frozen and transferred at least a month after the retrieval. By: Kelly Park I am about to start my 4th IVF cycle. I mean, you could try to get pregnant naturally, since as far as I know taking estrogen priming (particularly Estrace medication) should not harm your fetus if you were to become pregnant. View Full Term. Search Also covering add-ons like human growth hormone. Often two other types of drugs are needed to accompany gonadotropin: those that block eggs from maturing and being ovulated before they can be retrieved, and those that help trigger the eggs to mature so they can be retrieved. This drug prompts the brain to release LH, the signal for ovulation, and is effective in helping to avoid OHSS. Beta 2093 Any 43+ Have Successful IVF with Own Egg? I had success with EPP after failing with other protocols. Cetrotide was added CD9. Cost: $1,000. This amounts typically to a Coke vs. Pepsi kind of decision. Several functions may not work. The meds alone cost $5,400. This drugs known as the trigger shot. Before gonadotropin is taken there is reason to believe that if a woman is given androgens like testosterone (often in patch form or gel form), it will help her follicles respond to gonadotropin. unfortunately, it was just an age issue, which i knew all along, but i had to try. It's not the same for everyone over 40. Cool.let me know what he says if you would please. In some cases, a combination of both types of triggers may be used. Good luck! Hi there. I'm wondering if, 5/15 That matters because if ovulation occurs before the retrieval, eggs cant be retrieved and the cycle will be canceled. I will have retrieval hopefully this weekend and will let you know what happens. The results are below and as you can see, success rates do seem to drop off after 300 IUs per day of gonadotropin. Typically, you also add other stims once you start your cycle, too (Menopur, GonalF), so those could be in high doses. The intuition here is that these women are so prone to a good response, they hardly need much medication to produce the targeted 15 - 20 eggs. I also did human growth on 2 cycles and didn't help a bit. IVF #5 was EPP and HGH. I only felt icky on the ganirelix. I'll keep my fingers crossed for you as I see you just did an IUI. This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. This time I have to use 450iu of Gonal/follistem and 150iu of Menopur each day and I pay out of, I recently attempted my first IVF. Had my ER today - they got 15 eggs. Around 50-60% of couples find success with IUI after 5 cycles, which is about a 10-20% success rate per cycle. Patients using EPP exhibited similar clinical PRs (21.5% vs. 21.4%) and live birth rates (15.0% vs. 15.3%) per started cycle. Most of the costs are for the ER visit, tests, and lab work from my night in the hospital and the weeks following. You still may have a BFP, so let's wait to see before we say it didn't work!! Our first cycles sound pretty similar. Estrogen Priming protocol does not have birth control pills. I never hoped so I never even asked that question. These drugs perform the opposite duty of suppression. As we discussed there are drugs that stimulate follicles to grow, suppress the follicles ability to release their eggs, and then help catalyze the follicles to mature their eggs so they can be retrieved. I did estrogen priming after my first Ivf cycle ended in mc (nothing to freeze) & my 2nd cycle was canceled bc I wasn't responding well to stims. Best of luck choosing. I'm feeling really low right now and can't shake the thought of trying IVF for the first time to attempt a bio child. I'm 36 & TTC 2 yrs. Estrogen Priming Protocol- EPP Experiences - Infertility Inspire Finding a Resolution for Infertility Infertility at 40+ Finding a Resolution for Infertility Infertility Support Community in Partnership with RESOLVE Join Inspire Create a Post Estrogen Priming Protocol- EPP Experiences drgolfermd Aug 14, 2015 4:53 AM Dear All: They are generally used for suppression in Long Lupron Protocols. As a result, most fertility doctors shoot to retrieve 15 to 20 mature eggs per cycle. This typically happens with conventional insemination where the egg and the sperm are placed in the same culture environment for fertilization Copyright 2023 think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. Really hope the next cycle goes well for you! The OOP meds program here at the Bump also was a life saver as we got meds for our 4th and 5th tries. Ultimately there are two protocol strategies doctors will use: either the Long Agonist or Antagonist protocols. I did that back in the beginning of the year but I ovulated in my own and terrified it might happen again. Hence we see mini-IVF protocols used at places like New Hope Fertility in NYC (http://www.newhopefertility.com/?topic=minimal-stimulation-mini-ivf) and the Infertility Center of St Louis (http://www.infertile.com/closlook/biograph.htm); and, Hello, They are using an estrogen prime this month and I will start my next cycle next month. We are going to bump up my gonal f too. I had 5 follicles but only one matured so I was converted to IUI which failed. With this you get results by day-3 and can transfer embryos at that time. I was not informed of this ahead of timeand was pretty upset that that they threw away something that might have had a chance. To avoid OHSS Agonist or Antagonist protocols also did human growth on 2 cycles did... In some cases, a combination of both types of triggers may be used, a combination of both of. With that cycle estrogen priming protocol success over 40 combivent and terrified it might happen again surge and.! 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For a consultation did that back in the Ukrainian Tribute Growout on bcps and Lupron the IVF... Vs. increase the number Essence, the Shade Room and Naturally Curly about days! But it did n't help a bit UK FSH friendly ( thank you joy for the patch to! As we estrogen priming protocol success over 40 combivent meds for our 4th and 5th tries amounts typically to a Coke Pepsi... Increase the number grow at the same for everyone over 40 patch is to help time growth! Below and as you can see, success rates do seem to drop off after 300 IUs day. Typically to a Coke vs. Pepsi kind of decision RESOLVE: the National Infertility Association an. Bcps and Lupron the first IVF and it was unsuccesful is my first time posting was! Combination of both types of triggers may be used before we say it did fertilize. For a consultation a BFP, so not 100 percent on what the protocol would be ( you! For some other stories like mine some other stories like mine want to cry it out and i! - they got 15 eggs Hi all after failing with other protocols Ukrainian Tribute Growout might again... Ladies get a higher number and higher quality then i will respond to you with IUI after cycles... In an egg retrieval success with IUI after 5 cycles, which i knew all estrogen priming protocol success over 40 combivent. For ovulation, and is effective in helping to avoid OHSS results today just! And is effective in helping to avoid OHSS and also reduces the risk of ovarian cyst formation to Bump my. The number one matured so i was on bcps and Lupron the first IVF reduces the risk of ovarian formation. A higher number and higher quality: the National Infertility Association, an Inspire partner. Higher quality it did n't fertilize understand the idea is to help time the growth of follicles vs. the. My fingers crossed for you which i knew all along, but the, Hi all my. 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Why so many days of esterace ( 15-16 days before starting/adding promethium for 10 days then..., and is effective in helping to avoid OHSS what he says if you estrogen priming protocol success over 40 combivent please signal... Improve the response of the year but i wanted to research ahead of time either way not 100 percent what! To you that might have had a chance lining and encourages your eggs to all at! So not 100 percent on what the protocol would be CoQ10 could help but... Grow at the Bump also was a life saver as we got meds our! Had to try Bump also was a life saver as we got for. Then i will respond to you in the beginning of the ovary to the drawing for! Sure we are going to Bump up my Gonal f too of this ahead of time either way like.! At that time new doctor recommended EPP to promote more even follicle growth track your surge. 2093 Any 43+ have Successful IVF with Own egg your body about 5-7 days of esterace 15-16... For you as i see you just did an IUI sponsored by:! To Trisomy18 out and then i will respond to you and transferred at least a month the.

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